*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : DU3103000
CHEMICAL NAME : (2,2'-Binaphthalene)-8,8'-dicarboxaldehyde,
1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-
3,3'-dimethyl-, hexaacetate
CAS REGISTRY NUMBER : 30719-67-6
LAST UPDATED : 198910
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C42-H42-O14
MOLECULAR WEIGHT : 770.84
WISWESSER LINE NOTATION : L66J BY1&1 COV1 DOV1 EVH GOV1 I1 H- HL66J BY1&1 COV1
DOV1 EVH GOV1 I1
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* Gossypol acetate
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 1120 mg/kg
SEX/DURATION : male 28 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
REFERENCE :
CTSRCS Cell and Tissue Research. (Springer-Verlag New York, Inc., Service
Center, 44 Hartz Way, Secaucus, NJ 07094) V.148- 1974-
Volume(issue)/page/year: 204,293,1979
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 100 mg/kg
SEX/DURATION : female 20 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 32,491,1985
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - hamster
DOSE : 400 mg/kg
SEX/DURATION : female 20 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1-
1970- Volume(issue)/page/year: 24,259,1981
*** END OF RECORD ***