*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DU9085000
CHEMICAL NAME           : 4-Biphenylamine, 4,4'-dimethoxy-
CAS REGISTRY NUMBER     : 101-70-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C14-H15-N-O2
MOLECULAR WEIGHT        : 229.30
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Benzenamine, 4-methoxy-N-(4-methoxyphenyl)-
   * Bis(p-anisylamine)
   * Bis(p-methoxyphenyl)amine
   * Bis(4-methoxyphenyl)amine
   * Di-p-anisylamine
   * p,p'-Dimethoxydiphenylamine
   * 4,4'-Dimethoxydiphenylamine
   * Di-p-methoxyphenylamine
   * Termofleks A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2470 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   KCRZAE Kauchuk i Rezina.  Crude and Vulcanized Rubber.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR)  V.11-    1937- Volume(issue)/page/year:
   26(9),28,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   KCRZAE Kauchuk i Rezina.  Crude and Vulcanized Rubber.  (V/O Mezhdunarodnaya
   Kniga, 113095 Moscow, USSR)  V.11-    1937- Volume(issue)/page/year:
   26(9),28,1967
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 30 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 241,175,1990

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80320
       No. of Facilities: 96 (estimated)
       No. of Industries: 3
       No. of Occupations: 15
       No. of Employees: 1166 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***