*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DV1756000
CHEMICAL NAME           : (1,1'-Biphenyl)-4-butanoic acid,
                          2'-chloro-alpha-methylene-gamma-oxo-
CAS REGISTRY NUMBER     : 58182-63-1
BEILSTEIN REFERENCE NO. : 2138480
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H13-Cl-O3
MOLECULAR WEIGHT        : 300.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acide (chloro-2' biphenylyl-4)-4 methylene-2 oxo-4 butyrique
   * 2'-Chloro-alpha-methylene-gamma-oxo-(1,1'-biphenyl)-4-butanoic acid
   * F 1379
   * Itanoxone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 22,45,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 22,45,1987
 
                            *** END OF RECORD ***