*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DT4300000
CHEMICAL NAME           : (7,7'-Bi-1H-1,5-benzodiazepine)-2,2'-dicarbonitrile,
                          2,2',3,3',4,4',5,5'-octahydro-4,4'- dimethyl-
CAS REGISTRY NUMBER     : 87896-42-2
LAST UPDATED            : 198503
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H24-N6
MOLECULAR WEIGHT        : 372.52
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AN-21
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 665 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year: 35,89,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 613 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year: 35,89,1983
 
                            *** END OF RECORD ***