*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DV5075000
CHEMICAL NAME           : (1,1'-Biphenyl)-2,2'-diol,
                          5,5'-dichloro-3,3'-dinitro-
CAS REGISTRY NUMBER     : 10331-57-4
OTHER CAS REGISTRY NOS. : 11139-59-6
BEILSTEIN REFERENCE NO. : 2019644
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C12-H6-Cl2-N2-O6
MOLECULAR WEIGHT        : 345.10
WISWESSER LINE NOTATION : WNR DQ CG ER BQ CG ENW
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * BAY 9015
   * Bayer 9015
   * Bilevon M
   * o,o'-Biphenol, 3,3'-dichloro-5,5'-dinitro-
   * 5,5'-Dichloro-2,2'-dihydroxy-3,3'-dinitrobiphenyl
   * 3,3'-Dichloro-5,5'-dinitro-o,o'-biphenol
   * 4,4'-Dichloro-6,6'-dinitro-O,O'-biphenol
   * 5,5'-Dichloro-3,3'-dinitro(1,1'-biphenyl)-2,2'-diol
   * ME 3625
   * Menichlopholan
   * Niclofolan
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JETOAS Journal Europeen de Toxicologie.  (Paris, France)  V.1-6, 1968-72.
   For publisher information, see TOERD9.  Volume(issue)/page/year: 4,525,1971
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAZMAE Fortschritte der Arzneimittelforschung.  Progress in Drug Research.
   (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way,
   Secaucus, NJ 07094)  V.1-    1959-  Volume(issue)/page/year: 17,108,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 10 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   JETOAS Journal Europeen de Toxicologie.  (Paris, France)  V.1-6, 1968-72.
   For publisher information, see TOERD9.  Volume(issue)/page/year: 4,525,1971
 
                            *** END OF RECORD ***