*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : DT4750000
CHEMICAL NAME           : Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-phenyl-,
                          3-(diethylamino)propyl ester
CAS REGISTRY NUMBER     : 20448-86-6
LAST UPDATED            : 199203
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H31-N-O2
MOLECULAR WEIGHT        : 329.53
WISWESSER LINE NOTATION : L55 ATJ CVO3N2&2 CR
SYNONYMS/TRADE NAMES :
   * Bornaprine
   * KR 339
   * 2-Norbornanecarboxylic acid, 2-phenyl-, 3-(diethylamino)propyl ester
   * 2-Phenylbicyclo(2.2.1)heptan-2-carbonsaeure-(gamma-diaethylaminopropyl)  
   ester
   * 2-Phenyl-2-(gamma-diethylaminocarbopropoxy)-bicyclo(2.2.1)heptane
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 112 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 128,204,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 128,204,1960
 
                            *** END OF RECORD ***