*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : DT4780000 CHEMICAL NAME : Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-phenyl-, 2-(pyrrolidino)ethyl ester CAS REGISTRY NUMBER : 3570-06-7 BEILSTEIN REFERENCE NO. : 1689298 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H27-N-O2 MOLECULAR WEIGHT : 313.48 WISWESSER LINE NOTATION : L55 ATJ CR& CVO2- AT5NTJ SYNONYMS/TRADE NAMES : * Bicyclophenamine * KR 363 * 2-Norbornanecarboxylic acid, 1-phenyl-, 2-(1-pyrrolidinyl)ethyl ester * 2-Phenylbicyclo(2.2.1)heptan-2-carbonsaeure-(beta-pyrrolidinoaethyl) ester *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 308 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 38 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960 *** END OF RECORD ***