*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : EC5990500 CHEMICAL NAME : Bleomycinamide, N'-(3-((4-aminobutyl)amino)propyl)- CAS REGISTRY NUMBER : 11116-32-8 LAST UPDATED : 199506 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C57-H89-N19-O21-S2 MOLECULAR WEIGHT : 1440.77 WISWESSER LINE NOTATION : T6OTJ BQ CQ DOVZ EQ FO- CT6OTJ DQ EQ FQ BOY- DT5M CNJ&YVMY1&YQY1&VNYYQ1&VM2- BT5N CSJ E- COMPOUND DESCRIPTOR : Drug Mutagen Human SYNONYMS/TRADE NAMES : * N1-(3-((4-Aminobutyl)amino)propyl)bleomycinamide * Bleomycetin * Bleomycin A5 * Pingyangmycin * Zhengguangmycin A5 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human DOSE/DURATION : 192 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature increase REFERENCE : ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 28,632,1983 ** MUTATION DATA ** TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 40 mg/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 199,199,1988 TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - mouse Fibroblast DOSE/DURATION : 100 mg/L REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,878,1974 TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 400 ug/L REFERENCE : HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1981- Volume(issue)/page/year: 3,78,1983 TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 400 ug/L REFERENCE : HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1981- Volume(issue)/page/year: 3,78,1983 *** END OF RECORD ***