*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EC6046000
CHEMICAL NAME           : Blood-coagulation factor viii, complex
CAS REGISTRY NUMBER     : 9001-27-8
LAST UPDATED            : 199504
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Factorate
   * Factor VIII
   * Hemofil
   * Hemofil M
   * Profilate
   * Thromboplastinogen
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1320 units/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 15,801,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1320 units/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 15,801,1985

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5324
       No. of Facilities: 40 (estimated)
       No. of Industries: 2
       No. of Occupations: 5
       No. of Employees: 1716 (estimated)
       No. of Female Employees: 1209 (estimated)

 
                            *** END OF RECORD ***