*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : EC6065000 CHEMICAL NAME : Blood Preservative Solution, CPDA LAST UPDATED : 199509 DATA ITEMS CITED : 2 SYNONYMS/TRADE NAMES : * CPDA *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 12 mL/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - sensory change involving peripheral nerve Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 21,2043,1993 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 210 mL/kg/28D-I TOXIC EFFECTS : Brain and Coverings - changes in brain weight Cardiac - changes in heart weight Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 21,2047,1993 *** END OF RECORD ***