*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ED9540000
CHEMICAL NAME           : Bouvardin,
                          6-(3-hydroxy-N,O-dimethyl-L-tyrosine)-5-(N-methyl-L-t
                          yrosine)-
CAS REGISTRY NUMBER     : 86229-97-2
LAST UPDATED            : 199703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C41-H50-N6-O9
MOLECULAR WEIGHT        : 770.97
SYNONYMS/TRADE NAMES :
   * 6-(3-Hydroxy-N,O-dimethyl-L-tyrosine)-5-(N-methyl-L-tyrosine)bouvardin
   * Methylether of TPC-A
   * RA VII
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 32,3216,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 32,3216,1984
 
                            *** END OF RECORD ***