*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : EI2959000
CHEMICAL NAME : 5-beta-Bufa-20,22-dienolide,
3-beta-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,14-hyd
roxy-19- oxo-
CAS REGISTRY NUMBER : 20300-44-1
BEILSTEIN REFERENCE NO. : 0072412
REFERENCE : 4-18-00-03181 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C30-H42-O10
MOLECULAR WEIGHT : 562.72
WISWESSER LINE NOTATION : L E5 B666TJ AVH E1 IQ MQ F- ET6OVJ& OO- BT6OTJ CQ DQ
EQ F1
COMPOUND DESCRIPTOR : Natural Product
SYNONYMS/TRADE NAMES :
* Degluco-hellebrin
* Desgluco-hellebrin
* Hellebrigenin-L-rhamnosid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 86 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 90,271,1947
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 157 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APJUA8 Acta Pharmaceutica Jugoslavica. (FDH, Masarykova 2, 41000 Zagreb,
Yugoslavia) V.1-41, 1951-1991. Volume(issue)/page/year: 24,179,1974
*** REVIEWS ***
TOXICOLOGY REVIEW
85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster,
Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year:
-,190,1963
*** END OF RECORD ***