*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : EI3690000
CHEMICAL NAME : Bufa-4,20,22-trienolide,
3-beta-((beta-D-glucopyranosyl)oxy)-14-hydroxy-19-oxo
-
CAS REGISTRY NUMBER : 73309-75-8
LAST UPDATED : 199012
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C30-H40-O10
MOLECULAR WEIGHT : 560.70
WISWESSER LINE NOTATION : L E5 B666 MUTJ AVH E1 IQ F- ET6OVJ& OO- BT6OTJ CQ DQ
EQ F1Q
COMPOUND DESCRIPTOR : Mutagen
Natural Product
SYNONYMS/TRADE NAMES :
* Altosid
* Altoside
* 3-beta-((beta-D-Glucopyranosyl)oxy)-14-hydroxy-19-oxo-bufa-4,20,22-trien
olide
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 80 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster,
Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year:
-,188,1963
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 77 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster,
Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year:
-,70,1963
** MUTATION DATA **
TYPE OF TEST : Dominant lethal test
ROUTE OF EXPOSURE : Administration onto the skin
TEST SYSTEM : Insect - Drosophila melanogaster
DOSE/DURATION : 10 pph
REFERENCE :
CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK.
(Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974-
Volume(issue)/page/year: 13(6),37,1979
*** END OF RECORD ***