*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EC0874800
CHEMICAL NAME           : alpha,alpha'-Bi-p-toluic acid, ester with
                          2-methyl-1-piperidinepropanol, hydrochloride
LAST UPDATED            : 199512
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C34-H48-N2-O4.Cl-H
MOLECULAR WEIGHT        : 585.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bis(alpha-methylpiperidino-n-propyl) 4,4'-dibenzyldicarboxylate  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 175 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 45,382,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 19 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - local anesthetic
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 45,382,1956
 
                            *** END OF RECORD ***