*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EJ9965000
CHEMICAL NAME           : Butanedioic acid, 4'''-ester with
                          5-((O-2,6-dideoxy-3-O-methyl-alpha-L-lyxo-hexopyranos
                          yl-
                          (1-4)-O-2,3,6-trideoxy-3-C-methyl-3-nitro-beta-L-ribo
                          -hexopyranosyl-(1-4)- 2,3,6-trideoxy-3-
                          C-methyl-3-nitro-beta-L-ribo-hexopyranosyl)oxy)-4-(di
                          methylamino)-3,4,5,6, 11,12,13,14-
                          octahydro-3,10,13,15-tetrahydroxy-6,13-dimethyl-11-((
                          2,3,6-trideoxy-3-(dim ethylamino)-alpha-
                          L-lyxo-hexopyranosyl)oxy)-2,6-epoxy-2H-naphthaceno(1,
                          2-b)oxocin-9,16-dione, dihydrochloride
LAST UPDATED            : 199212
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C60-H82-N4-O26.2Cl-H
MOLECULAR WEIGHT        : 1348.38
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Decilorubicin dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 36,451,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 36,451,1983
 
                            *** END OF RECORD ***