*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : EK1610000 CHEMICAL NAME : 2,3-Butanediol, 1,4-dimercapto-, D-threo- CAS REGISTRY NUMBER : 3483-12-3 LAST UPDATED : 199707 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C4-H10-O2-S2 MOLECULAR WEIGHT : 154.26 WISWESSER LINE NOTATION : SH1YQYQ1SH -D,THREO COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)- * Cleland reagent * D-threo-1,4-Dimercapto-2,3-butanediol * (R*,R*)-1,4-Dimercapto-2,3-butanediol * 1,4-Dithiothreitol * D-1,4-Dithiothreitol * Sputolysin * Threitol, 1,4-dithio- * WR 34678 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 154 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1419,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 108 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 1,576,1949 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7467 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1196 (estimated) No. of Female Employees: 906 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***