*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK1610000
CHEMICAL NAME           : 2,3-Butanediol, 1,4-dimercapto-, D-threo-
CAS REGISTRY NUMBER     : 3483-12-3
LAST UPDATED            : 199707
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C4-H10-O2-S2
MOLECULAR WEIGHT        : 154.26
WISWESSER LINE NOTATION : SH1YQYQ1SH -D,THREO
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-
   * Cleland reagent
   * D-threo-1,4-Dimercapto-2,3-butanediol
   * (R*,R*)-1,4-Dimercapto-2,3-butanediol
   * 1,4-Dithiothreitol
   * D-1,4-Dithiothreitol
   * Sputolysin
   * Threitol, 1,4-dithio-
   * WR 34678
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 154 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 94,1419,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 108 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 1,576,1949

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X7467
       No. of Facilities: 68 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 1196 (estimated)
       No. of Female Employees: 906 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***