*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK7713440
CHEMICAL NAME           : Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)-,
                          (2S)-
CAS REGISTRY NUMBER     : 83730-53-4
BEILSTEIN REFERENCE NO. : 2367136
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H18-N2-O3-S
MOLECULAR WEIGHT        : 222.34
COMPOUND DESCRIPTOR     : Mutagen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * L-Buthionine sulfoximine
   * L-Buthionine-(S,R)-sulfoximine
   * NSC 326231
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3552 mg/kg
SEX/DURATION            : female 10-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 44,251,1991
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lung
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CBTOE2 Cell Biology and Toxicology.  (Princeton Scientific Pub., Inc., 301
   N. Harrison St., CN 5279, Princeton, NJ 08540)  V.1-    1984-
   Volume(issue)/page/year: 7,249,1991
 
                            *** END OF RECORD ***