*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK7713970
CHEMICAL NAME           : Butanoic acid,
                          1-butyl-2-((1-oxobutoxy)methyl)-3,4,5-piperidinetriyl
                          ester, (2R-(2alpha,3beta,4alpha,5beta))-
CAS REGISTRY NUMBER     : 131262-82-3
LAST UPDATED            : 199801
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C26-H45-N-O8
MOLECULAR WEIGHT        : 499.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Perbutylated-N-butyl-1-deoxynojiromycin
   * SC 49483
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 103 gm/kg/4W-I
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of salivary glands
   Gastrointestinal - changes in structure or function of endocrine pancreas
   Gastrointestinal - other changes
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 24,531,1996
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 218 gm/kg/26W-I
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of endocrine pancreas
   Gastrointestinal - other changes
   Endocrine - other changes
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 24,531,1996
 
                            *** END OF RECORD ***