*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EK7788500
CHEMICAL NAME           : Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-,
                          (hexahydro-1H-pyrrolizin-1-yl)methyl ester, N-oxide,
                          (1R-(1-alpha(2S*,3R*),7a-alpha))-
CAS REGISTRY NUMBER     : 510-19-0
LAST UPDATED            : 198803
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C15-H27-N-O5
MOLECULAR WEIGHT        : 301.43
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Trachelanthamine oxide
   * Trachelanthine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - muscle weakness
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 4(2),19,1941
 
                            *** END OF RECORD ***