*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EL6500000
CHEMICAL NAME           : 2-Butanone, 1-(N-acetonyl-N-nitrosoamino)-
CAS REGISTRY NUMBER     : 77698-20-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H12-N2-O3
MOLECULAR WEIGHT        : 172.21
WISWESSER LINE NOTATION : 2V1NNO&1V1
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * N-Nitroso(2-oxobutyl)(2-oxopropyl)amine
   * OBOB
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 174 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - olfactory nerve change
   Gastrointestinal - other changes
   Liver - other changes
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   12,223,1981
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   12,223,1981
 
                            *** END OF RECORD ***