*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EL6570000
CHEMICAL NAME           : 1-Butanone,
                          1-(2-amino-4-fluorophenyl)-4-(4-hydroxy-4-(3-(trifluo
                          romethyl)phenyl)-1- piperidinyl)-
CAS REGISTRY NUMBER     : 42048-72-6
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H24-F4-N2-O2
MOLECULAR WEIGHT        : 424.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-(3-(2-Amino-4-fluorobenzoyl)propyl)-4-hydroxy-4-(3-trifluoromethylphen
     yl)piperidine
   * ID-4708
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 780 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,1248,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 24,1248,1974
 
                            *** END OF RECORD ***