*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EM2750000
CHEMICAL NAME           : 2-Butenamide,
                          N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenz
                          o(a)heptalen-7-yl)-, (S)-
CAS REGISTRY NUMBER     : 99481-33-1
LAST UPDATED            : 198904
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H27-N-O6
MOLECULAR WEIGHT        : 425.52
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-Crotonyldeacetylcolchicine
   *   (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-
     yl)-2-butenamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1445 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNPRDF Journal of Natural Products.  (Spahr & Glenn Co., 225 E. Spring St.,
   Columbus, OH 43215) V.42-    1979-  Volume(issue)/page/year: 48,878,1985
 
                            *** END OF RECORD ***