*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EM4300000
CHEMICAL NAME           : 2-Butenediamide, N-(phenylacetyl)-, (E)-
CAS REGISTRY NUMBER     : 57687-92-0
BEILSTEIN REFERENCE NO. : 2506249
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H12-N2-O3
MOLECULAR WEIGHT        : 232.26
WISWESSER LINE NOTATION : ZV1U1VMV1R
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic C 9154
   * Fumaramidmycin
   * N-(Phenylacetyl)-2-butenediamide, (E)-
   * trans-N-(Phenylacetyl)-2-butenediamide
   * Ro 09-0049
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 28,636,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al.,
   eds., Washington, DC, American Soc. for Microbiology, 1978
   Volume(issue)/page/year: 1,759,1978
 
                            *** END OF RECORD ***