*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : EM4910000 CHEMICAL NAME : 2-Butene, 2,3-dichlorohexafluoro- CAS REGISTRY NUMBER : 303-04-8 LAST UPDATED : 199806 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C4-Cl2-F6 MOLECULAR WEIGHT : 232.94 WISWESSER LINE NOTATION : FXFFYGUYGXFFF SYNONYMS/TRADE NAMES : * 2-Butene, 2,3-dichloro-1,1,1,4,4,4-hexafluoro- * CFC 1316 * CFC 1316 mxx * Dchfb * 2,3-Dichlorohexafluorobutene-2 * 2,3-Dichloro-1,1,1,4,4,4-hexafluorobutene-2 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DOWCC* Dow Chemical Company Reports. (Dow Chemical USA, Health and Environment Research, Toxicology Research Lab., Midland, MI 48640) Volume(issue)/page/year: -,-,1963 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 16 ppm/4H TOXIC EFFECTS : Behavioral - general anesthetic Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis REFERENCE : BJANAD British Journal of Anesthesia. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1923- Volume(issue)/page/year: 37,716,1965 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 26 ppm/4H TOXIC EFFECTS : Behavioral - general anesthetic Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis REFERENCE : BJANAD British Journal of Anesthesia. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1923- Volume(issue)/page/year: 37,716,1965 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 182 ppm/4H TOXIC EFFECTS : Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Lungs, Thorax, or Respiration - acute pulmonary edema REFERENCE : JETOAS Journal Europeen de Toxicologie. (Paris, France) V.1-6, 1968-72. For publisher information, see TOERD9. Volume(issue)/page/year: 4,517,1971 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 54 ppm/3H TOXIC EFFECTS : Behavioral - ataxia Lungs, Thorax, or Respiration - changes in pulmonary vascular resistance Lungs, Thorax, or Respiration - consolidation REFERENCE : ANESAV Anesthesiology. (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1940- Volume(issue)/page/year: 26,140,1965 *** END OF RECORD ***