*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EN0705000
CHEMICAL NAME           : 3-Butenylamine,
                          N,N-dimethyl-4-phenyl-4-(alpha,alpha,alpha-trifluoro-
                          p-tolyl)-, hydrochloride
CAS REGISTRY NUMBER     : 4510-65-0
LAST UPDATED            : 199309
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C19-H20-F3-N.Cl-H
MOLECULAR WEIGHT        : 355.86
WISWESSER LINE NOTATION : FXFFR DYR&U3N1&1 &GH
SYNONYMS/TRADE NAMES :
   * BS 7308
   *   N,N-Dimethyl-4-phenyl-4-(alpha,alpha,alpha-trifluoro-p-tolyl)-3-butenyla
     mine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Liver - fatty liver degeneration
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 160,231,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Liver - fatty liver degeneration
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 160,231,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 630 mg/kg
TOXIC EFFECTS :
   Behavioral - food intake (animal)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 160,231,1966
 
                            *** END OF RECORD ***