*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EO3900000
CHEMICAL NAME           : tert-Butylamine, compd. with borane (1:1)
CAS REGISTRY NUMBER     : 7337-45-3
LAST UPDATED            : 199806
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C4-H14-B-N
MOLECULAR WEIGHT        : 87.00
WISWESSER LINE NOTATION : ZX1&1&1 &BHHH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Boron, trihydro(2-methyl-2-propanamine)-, (T-4)-
   * tert-Butylamine, compd. with BH3 (1:1)
   * tert-Butylamine borane
   * (tert-Butylamine) trihydroboron
   * 2-Methyl-2-propanamine compd. with borane (1:1)
   * 2-Propanamine, 2-methyl-, compd. with borane (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 96 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - other changes
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535836
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 69,1025,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 820 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0535834

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - A1308
       No. of Facilities: 88 (estimated)
       No. of Industries: 2
       No. of Occupations: 2
       No. of Employees: 243 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - A1308
       No. of Facilities: 3 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 22 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***