*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : ES5222000 CHEMICAL NAME : Butyramidoxime, 3-hydroxy-4-(alpha-naphthyloxy)-, hydrochloride CAS REGISTRY NUMBER : 35991-93-6 LAST UPDATED : 198910 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H16-N2-O3.Cl-H MOLECULAR WEIGHT : 296.78 WISWESSER LINE NOTATION : L66J BO1YQ1YZUNQ &GH COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Bradyl * Butanimidamide, N,3-dihydroxy-4-(1-naphthalenyloxy)-, hydrochloride * Chlorhydrate de (naphthyloxy-1)-4 hydroxy-3 butyramidoxime * N,3-Dihydroxy-4-(1-naphthalenyloxy)butaninidamide hydrochloride * 3-Hydroxy-4-(1-naphthyloxy)butyramidoxime hydrochloride * LL 1530 * Nadoxolol hydrochloride * 4-alpha-Naphthyloxy-3-hydroxy-butyramidoxim-hydrochlorid * 4-(alpha-Naphthyloxy)-3-hydroxybutyramidoxime hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Cardiac - pulse rate Cardiac - other changes REFERENCE : TOERD9 Toxicological European Research. (S.P.E., 10, Ave. de Messine, 75008 Paris, France) V.1- 1978- Volume(issue)/page/year: 4,163,1982 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Cardiac - other changes REFERENCE : TOERD9 Toxicological European Research. (S.P.E., 10, Ave. de Messine, 75008 Paris, France) V.1- 1978- Volume(issue)/page/year: 4,163,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2132113 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2132113 *** END OF RECORD ***