*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : ES6550000 CHEMICAL NAME : Butyric acid, 2-amino-4-(p-(bis(2-chloroethyl)amino)phenyl)- CAS REGISTRY NUMBER : 3688-35-5 BEILSTEIN REFERENCE NO. : 3215367 REFERENCE : 4-14-00-01721 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H20-Cl2-N2-O2 MOLECULAR WEIGHT : 319.26 WISWESSER LINE NOTATION : QVYZ2R DN2G2G COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * 2-Amino-4-(p-(bis(2-chloroethyl)amino)phenyl)butyric acid * Aminochlorambucil * alpha-Amino-gamma-(p-dichloroethylamino)phenylbutyric acid * alpha-Amino-gamma-p-(N,N-di-2-chloroethylamino)phenylbutyric acid * Benzenebutanoic acid, alpha-amino-4-(bis(2-chloroethyl)amino)- * CB 1385 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,192,1960 TYPE OF TEST : LD10 - Lethal Dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJCAAH European Journal of Cancer. (Oxford, UK) V.1-17(6), 1965-1981. For publisher information, see EJCODS. Volume(issue)/page/year: 10,667,1974 ** MUTATION DATA ** TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Unreported TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 10 mmol/L REFERENCE : ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 160,228,1969 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: D melanogaster Sex-linked lethal *** END OF RECORD ***