*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : ET4730500 CHEMICAL NAME : Butyric acid, 2-hydroxy-2-methyl-, 4-ester with 1,2,3,3a-beta,4,6a-beta,7,7a-alpha,10,11, 11a,11b-alpha-dodecahydro-1-alpha,2-alpha,4-beta,10-a lpha,11-beta-pentahyd roxy-3-alpha,8, 11a-beta-trimethyl-5H-1,11c-beta-(epoxymethano)phenan thro(10,1-bc)pyran-5- one CAS REGISTRY NUMBER : 1448-23-3 LAST UPDATED : 199209 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C25-H36-O10 MOLECULAR WEIGHT : 496.61 WISWESSER LINE NOTATION : T5 F6666/DS 3AAE S AX CO NOV IUTJ DQ GQ HQ J1 POVXQ2&1 R1 SQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Glarubin * Glaucarubin * Glaucarubina * Glaumeba * alpha-Kirondrin * beta-Kirondrin * MK-53 * Simarubaceae *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 8(2),172,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 114,307,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 28 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 8(2),172,1982 *** END OF RECORD ***