*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU4172000
CHEMICAL NAME           : Butyrophenone,
                          4'-fluoro-4-(octahydrospiro(naphthalene-2(1H),4'-pipe
                          ridin)-1'-yl)-, hydrochloride
CAS REGISTRY NUMBER     : 101221-64-1
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H34-F-N-O.Cl-H
MOLECULAR WEIGHT        : 408.05
WISWESSER LINE NOTATION : L66 CXTJ C-& DT6N DXTJ A3VR DF &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4'-Fluoro-4-(octahydrospiro(naphthalene-2(1H),4'-piperidin)-1'-yl)-butyr
     ophenone HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,62,1965
 
                            *** END OF RECORD ***