*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU4375000
CHEMICAL NAME           : Butyrophenone,
                          4'-fluoro-4-(4-piperidino-4-propionylpiperidino)-
CAS REGISTRY NUMBER     : 3781-28-0
BEILSTEIN REFERENCE NO. : 0495940
REFERENCE               : 5-22-12-00490 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C23-H33-F-N2-O2
MOLECULAR WEIGHT        : 388.58
WISWESSER LINE NOTATION : T6NTJ A- DT6NTJ A3VR DF& DV2
SYNONYMS/TRADE NAMES :
   * 1-Butanone,  
   1-(4-fluorophenyl)-4-(4'-(1-oxopropyl)(1,4'-bipiperidin)-1'-yl)-
   * Floropipeton
   * 4'-Fluoro-4-(4-piperidino-4-propionylpiperidino)butyrophenone
   * Propyperone
   * R 4082
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 780 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,192,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,192,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,192,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 420 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,192,1972
 
                            *** END OF RECORD ***