*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU5200000
CHEMICAL NAME           : Butyrophenone,
                          2',2''',4',6',6'''-pentahydroxy-4'''-methoxy-3',3'''-
                          methylenebis(5'-methy l-
CAS REGISTRY NUMBER     : 1867-82-9
BEILSTEIN REFERENCE NO. : 2067959
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C24-H30-O8
MOLECULAR WEIGHT        : 446.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Margaspidin
   * Margaspidin BB
   * Margaspindin
   *   2',2''',4',6',6'''-Pentahydroxy-4'''-methoxy-3',3'''-methylenebis(5'-met
     hylbutyrophenone)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 31,247,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 54,1362,1965
 
                            *** END OF RECORD ***