*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU9850000
CHEMICAL NAME           : Cadmium, bis(diethyldithiocarbamato)-
CAS REGISTRY NUMBER     : 14239-68-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 32
MOLECULAR FORMULA       : C10-H20-Cd-N2-S4
MOLECULAR WEIGHT        : 408.96
WISWESSER LINE NOTATION : 2N2&YUS&S 2-CD-
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Bis(diethyldithiocarbamato)cadmium
   * Cadmate
   * Cadmium di(diethyldithiocarbamate)
   * Cadmium diethyl dithiocarbamate
   * Carbamic acid, diethyldithio-, cadmium salt
   * Cd diethyldithiocarbamate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ACLSCP Annals of Clinical and Laboratory Science.  (1833 Delancey Pl.,
   Philadelphia, PA 19103) V.1-    1971-  Volume(issue)/page/year: 11,476,1981
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7100 mg/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 68,313,1979
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 umol/L
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   46,277,1980

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.01 mg(Cd)/m3, inhalable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.002 mg(Cd)/m3, respirable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Suspected human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Human Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   IARC Cancer Review:Group 1
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.2 mg(Cd)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,34,1971

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.01 mg(Cd)/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993
   
   OEL-GERMANY;Carcinogen JAN 1993
   
   OEL-INDIA:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-JAPAN:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.02 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.2 mg(Cd)/m3 JAN 1993
   
   OEL-RUSSIA:TWA 0.01 mg(Cd)/m3;STEL 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993
   
   OEL-SWITZERLAND:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-THAILAND:TWA 0.2 mg(Cd)/m3;STEL 0.5 mg(Cd)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.2 mg(Cd)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.01 mg(Cd)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO CADMIUM, dust and fume-air:CA lowest feasible conc.
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***