*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EV1290000
CHEMICAL NAME           : Cadmium iodide
CAS REGISTRY NUMBER     : 7790-80-9
LAST UPDATED            : 199806
DATA ITEMS CITED        : 34
MOLECULAR FORMULA       : Cd-I2
MOLECULAR WEIGHT        : 366.20
COMPOUND DESCRIPTOR     : Tumorigen
                          Reproductive Effector
                          Human
SYNONYMS/TRADE NAMES :
   * Cadmium diiodide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 81 mg/kg
TOXIC EFFECTS :
   Liver - other changes
   Kidney, Ureter, Bladder - urine volume increased
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   ATXKA8 Archiv fuer Toxikologie.  (Berlin, Fed. Rep. Ger.)  V.15-31, 1954-74.
    For publisher information, see ARTODN.  Volume(issue)/page/year: 28,46,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 222 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 166 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   41HTAH "Aktual'nye Problemy Gigieny Truda.  Current Problems of Labor
   Hygiene," Tarasenko, N.Y., ed., Moscow, Pervyi Moskovskii Meditsinskii
   Inst., 1978  Volume(issue)/page/year: -,14,1978
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 200 mg/kg/29W-I
TOXIC EFFECTS :
   Liver - hepatitis (hepatocellular necrosis), zonal
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   KHZDAN Khigiena i Zdraveopazvane.  Hygiene and Sanitation.  (Hemus, Blvd.
   Russki 6, Sofia, Bulgaria) V.9-    1966-  Volume(issue)/page/year:
   9,142,1966
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 62 mg/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - maternal-fetal exchange
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 50(8),11,1985
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 62 mg/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 50(8),11,1985

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.01 mg(Cd)/m3, inhalable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.002 mg(Cd)/m3, respirable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Suspected human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Human Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   IARC Cancer Review:Group 1
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.2 mg(Cd)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,34,1971

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-AUSTRALIA:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.01 mg(Cd)/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993
   
   OEL-GERMANY;Carcinogen JAN 1993
   
   OEL-INDIA:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-JAPAN:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.02 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.2 mg(Cd)/m3 JAN 1993
   
   OEL-RUSSIA:TWA 0.01 mg(Cd)/m3;STEL 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-SWEDEN:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993
   
   OEL-SWITZERLAND:TWA 0.05 mg(Cd)/m3 JAN 1993
   
   OEL-THAILAND:TWA 0.2 mg(Cd)/m3;STEL 0.5 mg(Cd)/m3 JAN 1993
   
   OEL-TURKEY:TWA 0.2 mg(Cd)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.01 mg(Cd)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 81748
       No. of Facilities: 14 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 238 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 81748
       No. of Facilities: 7 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 7 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***