*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EV1925000
CHEMICAL NAME           : Cadmium oxide
CAS REGISTRY NUMBER     : 1306-19-0
LAST UPDATED            : 199806
DATA ITEMS CITED        : 70
MOLECULAR FORMULA       : Cd-O
MOLECULAR WEIGHT        : 128.40
WISWESSER LINE NOTATION :  CD  O
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
                          Reproductive Effector
                          Human
SYNONYMS/TRADE NAMES :
   * Cadmium monoxide
   * Cadmium oxide
   * Kadmu tlenek
   * NCI-C02551
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human
DOSE/DURATION           : 8630 ug/m3/5H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 22,455,1980
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 500 ug/m3/5Y-I
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - change in sensation of smell
   Kidney, Ureter, Bladder - proteinuria
REFERENCE :
   QJMEA7 Quarterly Journal of Medicine.  (Oxford Univ. Press, Walton St.,
   Oxford OX2 6DP, UK) V.1-    1932-  Volume(issue)/page/year: 38,425,1969
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 40 ug/m3
TOXIC EFFECTS :
   Cardiac - change in rate
   Vascular - BP elevation not characterized in autonomic section
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 45(10),22,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 22,455,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZDKAA8 Zdravookhranenie Kazakhstana.  Public Health of Kazakhstan.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1941-
   Volume(issue)/page/year: 38(9),18,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   41HTAH "Aktual'nye Problemy Gigieny Truda.  Current Problems of Labor
   Hygiene," Tarasenko, N.Y., ed., Moscow, Pervyi Moskovskii Meditsinskii
   Inst., 1978  Volume(issue)/page/year: -,14,1978
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/m3/2H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 94 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 4 gm/m3/10M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 1500 mg/m3/10M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2500 mg/m3/10M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 3500 mg/m3/10M
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85PDAD "Evaluation of the Impact of Cadmium on the Health of Man", Oxford,
   UK.  Pergamon Press Ltd., 1978  Volume(issue)/page/year: -,67,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HYSAAV Hygiene and Sanitation (USSR).  English translation of GISAAA.
   (Springfield, VA)  1964-71. Discontinued.  Volume(issue)/page/year:
   33(7-9),187,1968
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 156 ug/kg/26W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - proteinuria
   Blood - other changes
   Musculoskeletal - other changes
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(6),70,1987
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 23 ug/m3/24H/20W-C
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - proteinuria
   Musculoskeletal - osteoporosis
   Nutritional and Gross Metabolic - changes in calcium
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 52(5),85,1987
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 57 ug/m3/90D-C
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - changes in lung weight
   Blood - pigmented or nucleated red blood cells
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - phosphatases
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   40,231,1978
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 ug/m3/6H/2W-I
TOXIC EFFECTS :
   Cardiac - changes in heart weight
   Lungs, Thorax, or Respiration - other changes
   Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NIH-95-3388
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 ug/m3/6H/2W-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
   Lungs, Thorax, or Respiration - changes in lung weight
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NIH-95-3388
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 ug/m3/6H/13W-C
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - other changes
   Endocrine - changes in spleen weight
   Endocrine - changes in thymus weight
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NIH-95-3388
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   20,190,1966
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 21640 ug/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - maternal-fetal exchange
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 50(8),11,1985
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 21640 ug/kg
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 50(8),11,1985
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 183 ug/m3/5H
SEX/DURATION            : female 21 week(s) pre-mating
                          female 1-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - viability index (e.g., # alive at day 4
   per # born alive)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 22,53,1984
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 23 ug/m3/5H
SEX/DURATION            : female 21 week(s) pre-mating
                          female 1-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - behavioral
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 22,53,1984
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 91 ug/m3
SEX/DURATION            : female 1-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 31(8),25,1987
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2 mg/m3/6H
SEX/DURATION            : female 4-19 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NIH-95-3388
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 16 ug/m3/24H
SEX/DURATION            : female 1-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 46(10),13,1981
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2 mg/m3/6H
SEX/DURATION            : female 4-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NIH-95-3388
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 500 ug/m3/6H
SEX/DURATION            : female 4-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NIH-95-3388

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.01 mg(Cd)/m3, inhalable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 0.002 mg(Cd)/m3, respirable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Suspected human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 2,74,1973

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 11,39,1976

   IARC Cancer Review:Animal Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   IARC Cancer Review:Human Limited Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 11,39,1976

   IARC Cancer Review:Human Sufficient Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   IARC Cancer Review:Group 1
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 58,119,1993

   TOXICOLOGY REVIEW
   FCTXAV Food and Cosmetics Toxicology.  (London, UK)  V.1-19, 1963-81.  For
   publisher information, see FCTOD7.  Volume(issue)/page/year: 9,105,1971

   TOXICOLOGY REVIEW
   PEXTAR Progress in Experimental Tumor Research.  (S. Karger AG, Postfach
   CH-4009 Basel, Switzerland) V.1-    1960-  Volume(issue)/page/year:
   12,102,1969

   TOXICOLOGY REVIEW
   AMPMAR Archives des Maladies Professionnelles de Medecine du Travail et de
   Securite Sociale.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.7-    1946-
   Volume(issue)/page/year: 34,127,1973

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 0.05 mg/m3;Carcinogen (fume) JAN 1993
   
   OEL-BELGIUM:STEL 0.05 mg/m3;Carcinogen (fume) JAN 1993
   
   OEL-BELGIUM:TWA 0.05 mg/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.01 mg/m3 (fume) JAN 1993
   
   OEL-FINLAND:TWA 0.01 mg/m3;Carcinogen (fume) JAN 1993
   
   OEL-FINLAND;Carcinogen JAN 1993
   
   OEL-FRANCE:STEL 0.05 mg/m3 (fume) JAN 1993
   
   OEL-FRANCE:TWA 0.05 mg/m3 JAN 1993
   
   OEL-GERMANY;Carcinogen JAN 1993
   
   OEL-HUNGARY:STEL 0.05 mg/m3;Carcinogen JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.05 mg/m3 (fume) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.1 mg/m3 (fume) JAN 1993
   
   OEL-POLAND:TWA 0.1 mg/m3 (fume) JAN 1993
   
   OEL-SWITZERLAND:TWA 0.05 mg/m3 (fume) JAN 1993
   
   OEL-THAILAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3 (fume) JAN 1993
   
   OEL-TURKEY:TWA 0.1 mg/m3 (fume) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.05 mg/m3;STEL 0.5 mg/m3 (fume) JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO CADMIUM, dust and fume-air:CA lowest feasible conc.
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1554
       No. of Facilities: 1127 (estimated)
       No. of Industries: 37
       No. of Occupations: 28
       No. of Employees: 10110 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M1554
       No. of Facilities: 556 (estimated)
       No. of Industries: 27
       No. of Occupations: 31
       No. of Employees: 15727 (estimated)
       No. of Female Employees: 4850 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Cadmium and compounds, as Cd, 7048
   
   NTP 7th Annual Report on Carcinogens, 1992 : anticipated to be carcinogen
   
   NTP Toxicity studies, RPT# TOX-39, October 1997

 
                            *** END OF RECORD ***