*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : EW8750000 CHEMICAL NAME : Calotropin CAS REGISTRY NUMBER : 1986-70-5 LAST UPDATED : 199210 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C29-H40-O9 MOLECULAR WEIGHT : 532.69 WISWESSER LINE NOTATION : L E5 B666TJ AVH DQ E1 IQ F- DT5OV EHJ& O- BT6O CVTJ DQ EQ F1 COMPOUND DESCRIPTOR : Drug Natural Product SYNONYMS/TRADE NAMES : * Pecilocerin A * Pekilocerin A *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 9800 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : 41CIAR "Effects of Poisonous Plants on Livestock, Proceedings of a Joint U.S.-Australian Symposium on Poisonous Plants, Logan, UT, 1977," Keeler, R.F., et al. eds., New York, Academic Press, Inc., 1978 Volume(issue)/page/year: -,273,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 103 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,223,1942 *** END OF RECORD ***