*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EY8555800
CHEMICAL NAME           : Carbamic acid,
                          (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridiny
                          l)-, ethyl ester, (Z)-2-butenedioate (1:1)
CAS REGISTRY NUMBER     : 75507-68-5
OTHER CAS REGISTRY NOS. : 56995-21-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H17-F-N4-O2.C4-H4-O4
MOLECULAR WEIGHT        : 420.44
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (2-Amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)carbamic acid  
   ethyl ester maleate
   * D 9998 maleate
   * Ethyl-N-(2-amino-6-(4-fluorophenylmethylamino)pyridin-3-yl)carbamate  
   maleate
   * Ethyl-N-(2-amino-6-(4-fluor-phenylmethylamino)pyridin-3-yl)carbamat  
   maleat
   * Flupirtine maleate
   * Flupirtin-maleat
   * Katadolon
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1660 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 35,30,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 603 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 35,30,1985
 
                            *** END OF RECORD ***