*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EZ8740750
CHEMICAL NAME           : Carbamic acid, ((dimethylamino)methylene)-,
                          (6-(((dimethylamino)methylene)amino)-
                          1,1a,2,4,7,8,8a,8b-octahydro-8a-hydroxy-1,5-dimethyl-
                          4,7-dioxoazirino(2',3 ':3,4)pyrrolo(1,2-
                          a)indol-8-yl)methyl ester,
                          (1aS-(1a-alpha,8-alpha,8b-alpha))-
CAS REGISTRY NUMBER     : 105551-81-3
LAST UPDATED            : 199703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H28-N6-O5
MOLECULAR WEIGHT        : 444.55
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 7-N,N(sup 10)-Bis(dimethylaminomethylene)mitomycin D
   * Mitomycin D, 7-N,N(sup 10)-bis(dimethylaminomethylene)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EPXXDW European Patent Application. (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #0191375
 
                            *** END OF RECORD ***