*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : FA4550000
CHEMICAL NAME : Carbamic acid, dipropylthio-, S-ethyl ester
CAS REGISTRY NUMBER : 759-94-4
BEILSTEIN REFERENCE NO. : 1762751
REFERENCE : 4-04-00-00487 (Beilstein Handbook Reference)
LAST UPDATED : 199701
DATA ITEMS CITED : 21
MOLECULAR FORMULA : C9-H19-N-O-S
MOLECULAR WEIGHT : 189.35
WISWESSER LINE NOTATION : 3N3&VS2
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
Human
SYNONYMS/TRADE NAMES :
* S-Aethyl-N,N-dipropylthiolcarbamat
* Alirox
* Carbamothioic acid, dipropyl-, S-ethyl ester
* Dipropylcarbamothioic acid S-ethyl ester
* N,N-Dipropylthiocarbamic acid S-ethyl ester
* Eptam
* Eptam 6E
* EPTC
* S-Ethyldipropylthiocarbamate
* S-Ethyl-N,N-dipropylthiocarbamate
* S-Ethyl N,N-di-n-propylthiocarbamate
* Ethyl di-n-propylthiolcarbamate
* Ethyl-N,N-dipropylthiolcarbamate
* Ethyl N,N-di-n-propylthiolcarbamate
* FDA 1541
* Genep EPTC
* Niptan
* R-1608
* Stauffer R 1608
* Torbin
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Human
DOSE/DURATION : 135 mg/m3/90M
TOXIC EFFECTS :
Behavioral - headache
Behavioral - withdrawal
Gastrointestinal - nausea or vomiting
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
36(1-3),196,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 916 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB82-913299
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 200 mg/m3/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Behavioral - somnolence (general depressed activity)
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
36(1-3),196,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 36(2),29,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 3,618,1975
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
36(1-3),196,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 58 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
20037) V.1- 1953- Volume(issue)/page/year: 25,404,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#03907
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 112 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
36(1-3),196,1971
TYPE OF TEST : LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 400 mg/m3/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Behavioral - somnolence (general depressed activity)
Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.
(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:
36(1-3),196,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 2640 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1020,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1460 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71.
Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 1660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 45(5),29,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - wild bird species
DOSE/DURATION : 100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
21,315,1972
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 5 mg/L
REFERENCE :
GNKAA5 Genetika (Moscow). For English translation, see SOGEBZ. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1965-
Volume(issue)/page/year: 22,2416,1986
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-RUSSIA:STEL 2 mg/m3 JAN 1993
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84803
No. of Facilities: 18 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 684 (estimated)
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Negative: N crassa-aneuploidy
EPA TSCA Section 8(b) CHEMICAL INVENTORY
On EPA IRIS database
*** END OF RECORD ***