*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FB1440000
CHEMICAL NAME           : Carbamic acid, (2-(heptyloxy)phenyl)-,
                          2-(1-piperidinyl)ethyl ester, monohydrochloride
CAS REGISTRY NUMBER     : 55792-21-7
LAST UPDATED            : 199403
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C21-H34-N2-O3.Cl-H
MOLECULAR WEIGHT        : 399.03
WISWESSER LINE NOTATION : T6NTJ A2OVMR BO7 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Heptacaine
   * 2-Heptyloxycarbanilic acid 2-(1-piperidinyl)ethyl ester hydrochloride
   * (2-(Heptyloxy)phenyl)carbamic acid 2-(1-piperidinyl)ethyl ester  
   hydrochloride
   * N-(2-(Heptyloxyphenylcarbamoyloxy)ethyl)piperidinium chloride
   * Piperidinoethyl 2-heptoxyphenylcarbamoate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AFPCAG Acta Facultatis Pharmaceuticae, Universitatis Comenianae.  (Ustredna
   Kniznica Farmaceuticka Fakulta Univerzity Komenskeho, Sasinkova 5, 886 34
   Bratislava, Czechoslovakia)  V.14-    1967-  Volume(issue)/page/year:
   29,81,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AFPCAG Acta Facultatis Pharmaceuticae, Universitatis Comenianae.  (Ustredna
   Kniznica Farmaceuticka Fakulta Univerzity Komenskeho, Sasinkova 5, 886 34
   Bratislava, Czechoslovakia)  V.14-    1967-  Volume(issue)/page/year:
   29,53,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AFPCAG Acta Facultatis Pharmaceuticae, Universitatis Comenianae.  (Ustredna
   Kniznica Farmaceuticka Fakulta Univerzity Komenskeho, Sasinkova 5, 886 34
   Bratislava, Czechoslovakia)  V.14-    1967-  Volume(issue)/page/year:
   29,81,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 204 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DMDIEQ Drug Metabolism and Drug Interactions.  (Freund Publishing House,
   Suite 500, Chesham House, 150 Regent Street, London, W1R 5FA, United
   Kingdom)  V.6-    1988-  Volume(issue)/page/year: 9,321,1991
 
                            *** END OF RECORD ***