*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FB3850000
CHEMICAL NAME           : Carbamic acid, (mercaptoacetyl)methyl-, ethyl ester,
                          S-ester with O,O- diethyl phosphorodithioate
CAS REGISTRY NUMBER     : 2595-54-2
BEILSTEIN REFERENCE NO. : 1888011
LAST UPDATED            : 199710
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C10-H20-N-O5-P-S2
MOLECULAR WEIGHT        : 329.40
WISWESSER LINE NOTATION : 2OVN1&V1SPS&O2&O2
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
SYNONYMS/TRADE NAMES :
   * AFOS
   * O,O-Diaethyl-S-(3-methyl-2,4-dioxo-5-oxa-3-aza-heptyl)-dithiophosphat
   * O,O-Diethyl S-(N-ethoxycarbonyl-N-methylcarbamoylmethyl)  
   phosphorodithioate
   * O,O-Diethyl S-(N-ethoxycarbonyl-N-methylcarbamoylmethyl)  
   phosphorothiolothionate
   * O,O-Diethyl S-(N-methyl-N-carboethoxycarbamoylmethyl) dithiophosphate
   * O,O-Diethyl-S-(3-methyl-2,4-dioxo-5-oxa-3-aza-heptyl)-dithiofosfaat
   * O,O-Dietil-S-(N-etossi-carbonil-N-metil-carbamoil-metil)-ditiofosfato
   * Dithiophosphate de O,O-diethyle et de S-N-methyl N-carboethoxy  
   carbamoylmethyle
   * N-Ethoxycarbonyl-N-methylcarbamoylmethyl O,O-diethyl phosphorodithioate
   * S-((Ethoxycarbonyl)methylcarbamoyl)methyl O,O-diethyl phosphorodithioate
   * S-(N-Ethoxycarbonyl-N-methylcarbamoylmethyl)-diethyl phosphorodithioate
   * Marfotoks
   * MC 474
   * Mecarbam
   * Mecarbame
   * MS 1053
   * MS 1143
   * Murfotox
   * P 474
   * Pennsalt TD-72
   * Pestan
   * TD 72
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 31 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BOCKAF Bochu Kagaku.  Scientific Pest Control.  (Kyoto, Japan)  V.1-42,
   1937-77.  Discontinued.  Volume(issue)/page/year: 26,69,1961
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/m3/6H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PEMNDP Pesticide Manual.  (The British Crop Protection Council, 20 Bridport
   Rd., Thornton Heath CR4 7QG, UK)  V.1-    1968-  Volume(issue)/page/year:
   9,538,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 380 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 9,119,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 36 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
   New York, Inc., 1971  Volume(issue)/page/year: -,364,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 106 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,323,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BOCKAF Bochu Kagaku.  Scientific Pest Control.  (Kyoto, Japan)  V.1-42,
   1937-77.  Discontinued.  Volume(issue)/page/year: 26,69,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 65 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BOCKAF Bochu Kagaku.  Scientific Pest Control.  (Kyoto, Japan)  V.1-42,
   1937-77.  Discontinued.  Volume(issue)/page/year: 26,69,1961
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JEENAI Journal of Economic Entomology.  (Entomological Soc. of America, 4603
   Calvert Rd., College Park, MD 20740)  V.1-    1908- Volume(issue)/page/year:
   62,934,1969

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: B subtilis rec assay
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***