*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FB9895000
CHEMICAL NAME           : Carbamic acid, N-methyl-, 3-(dimethylamino)phenyl
                          ester, hydrochloride
CAS REGISTRY NUMBER     : 63982-40-1
LAST UPDATED            : 199209
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H14-N2-O2.Cl-H
MOLECULAR WEIGHT        : 230.72
WISWESSER LINE NOTATION : 1N1&R COVM1 &GH
SYNONYMS/TRADE NAMES :
   * AR-12
   * Methylcarbamic ester of 3-oxyphenyldimethylamine hydrochloride
   * N-Methylurethane of hydrochloride of 3-dimethylaminophenol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JCSOA9 Journal of the Chemical Society.  (London, UK)  1926-65.  For
   publisher information, see JCPRB4.  Volume(issue)/page/year: -,182,1947
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JCSOA9 Journal of the Chemical Society.  (London, UK)  1926-65.  For
   publisher information, see JCPRB4.  Volume(issue)/page/year: -,182,1947
 
TYPE OF TEST            : LD80 - Lethal Dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - other (direct) parasympathomimetic
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
                            *** END OF RECORD ***