*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FC9350000
CHEMICAL NAME           : Carbamic acid, N-nitroso-N-propyl-, ethyl ester
CAS REGISTRY NUMBER     : 19935-86-5
BEILSTEIN REFERENCE NO. : 1778057
REFERENCE               : 1-04-00-00367 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C6-H12-N2-O3
MOLECULAR WEIGHT        : 160.20
WISWESSER LINE NOTATION : ONN3&VO2
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Propyl-N-nitrosourethan
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1680 mg/kg/6W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   46,423,1982
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1370 mg/kg/29W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   67,549,1976
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Fibroblast
DOSE/DURATION           : 30 mg/L/20H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 48,337,1977
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 19 mg/L
REFERENCE :
   GMCRDC Gann Monograph on Cancer Research.  (Plenum Pub. Corp., 233 Spring
   St., New York, NY 10013) No. 11-    1971-  Volume(issue)/page/year:
   27,95,1981
 
                            *** END OF RECORD ***