*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : FD0406800 CHEMICAL NAME : Carbamic acid, (3-(pentyloxy)phenyl)-, 2-(1-pyrrolidinyl)cyclohexyl ester, monohydrochloride, trans-(+-)- CAS REGISTRY NUMBER : 77656-21-4 LAST UPDATED : 199403 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H34-N2-O3.Cl-H MOLECULAR WEIGHT : 411.04 COMPOUND DESCRIPTOR : Drug Reproductive Effector SYNONYMS/TRADE NAMES : * Pentacaine hydrochloride * Pentakain hydrochlorid *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 47 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DMDIEQ Drug Metabolism and Drug Interactions. (Freund Publishing House, Suite 500, Chesham House, 150 Regent Street, London, W1R 5FA, United Kingdom) V.6- 1988- Volume(issue)/page/year: 9,321,1991 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE : 150 mg/kg SEX/DURATION : female 6-20 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : CEFYAD Ceskoslovenska Fysiologie. (Academia, Vodickova 40, 112 29 Prague 1, Czechoslovakia) V.1- 1952- Volume(issue)/page/year: 38,278,1989 *** END OF RECORD ***