*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : FD0575000 CHEMICAL NAME : Carbamic acid, 2-phenylhydrazide CAS REGISTRY NUMBER : 103-03-7 BEILSTEIN REFERENCE NO. : 0743311 REFERENCE : 4-15-00-00180 (Beilstein Handbook Reference) LAST UPDATED : 199707 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C7-H9-N3-O MOLECULAR WEIGHT : 151.19 WISWESSER LINE NOTATION : ZVMMR COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * 1-Carbamoyl-2-phenylhydrazine * Carbaphen * Cryogenine (pharmaceutical) * Febrimin * Fenylsemikarbazid * Hydrazine, 1-carbamoyl-2-phenyl- * Hydrazinecarboxamide, 2-phenyl- * Phenicarbazid * Phenicarbazide * 2-Phenyldiazenecarboxamide * 2-Phenylhydrazide, carbamic acid * 1-Phenylhydrazine carboxamide * 2-Phenylhydrazinecarboxamide * Phenylsemicarbazide * 1-Phenylsemicarbazide * Semicarbazide, 1-phenyl- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 198 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 41,1469,1981 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 394 mg/kg/62W-C TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors REFERENCE : JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 52,241,1974 ** MUTATION DATA ** TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 250 ug/well REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 133,161,1984 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,177,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 12,177,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***