*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FD3097900
CHEMICAL NAME           : Carbamimidothioic acid,
                          1-((2-oxo-1-pyrrolidinyl)methyl)-2-(1-piperidinyl)eth
                          yl ester, dihydrochloride
CAS REGISTRY NUMBER     : 117039-07-3
LAST UPDATED            : 198909
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H24-N4-O-S.2Cl-H
MOLECULAR WEIGHT        : 357.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (1-N-Pyrrolidinoyl-3-piperidino)propyl-2-isothiouronium dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 96600 ug/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 22,563,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 152 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 22,563,1988
 
                            *** END OF RECORD ***