*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : FD7688000 CHEMICAL NAME : Carbanilic acid, p-carboxy-, 1,1'-trimethylenebis(2-(diethylamino)ethyl) ester, dihydrochloride LAST UPDATED : 198606 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C31-H44-N4-O8.2Cl-H MOLECULAR WEIGHT : 673.71 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * p-Carboxycarbanilic acid 1,1'-trimethylenebis(2-(diethylamino)ethyl) ester dihydrochloride * McN-100 dihydrochloride * Tridiurecaine dihydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Behavioral - sleep Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,421,1950 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 99,421,1950 *** END OF RECORD ***