*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FD8412000
CHEMICAL NAME           : Carbanilic acid, 2-chloro-6-methyl-,
                          2-(diethylamino)ethyl ester, hydrochloride
CAS REGISTRY NUMBER     : 20228-97-1
LAST UPDATED            : 199409
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H21-Cl-N2-O2.Cl-H
MOLECULAR WEIGHT        : 321.28
WISWESSER LINE NOTATION : GR C1 BMVO2N2&2 &GH
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * C 3069
   * 2-Chloro-6-methylcarbanilic acid 2-(diethylamino)ethyl ester  
   hydrochloride
   * 2-(Diethylamino)ethyl 2-chloro-6-methylcarbanilate hydrochloride
   * K 487
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2%
REACTION SEVERITY       : Mild
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,664,1958
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,664,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 16,316,1967
 
                            *** END OF RECORD ***