*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AI1540000
CHEMICAL NAME           : Acetic acid, hydroxy-,
                          7-cyano-9-(((1,2-dioxopropyl)amino)methyl)-1,5,6,7,9,
                          14,14a,15-
                          octahydro-10-hydroxy-2,11-dimethoxy-3,12,16-trimethyl
                          -1,4-dioxo-6,15-imino -4H-isoquino(3,2-b)
                          (3)benzazocin-13-yl ester,
                          (6S-(6-alpha,7-alpha,9-beta,14a-alpha,15-alpha))-
CAS REGISTRY NUMBER     : 106209-14-7
LAST UPDATED            : 199209
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C31-H34-N4-O10
MOLECULAR WEIGHT        : 622.69
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Saframycin R
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 26 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 35,1708,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 35,1708,1982
 
                            *** END OF RECORD ***