*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AJ1440000
CHEMICAL NAME           : Acetic acid,
                          oxo((7-oxo-1,3,5-cycloheptatrien-1-yl)amino)-, ethyl
                          ester
CAS REGISTRY NUMBER     : 65425-48-1
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H11-N-O4
MOLECULAR WEIGHT        : 221.23
WISWESSER LINE NOTATION : T7OJ BMO1VO2
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * AY-25,674
   * N-(2-Oxo-3,5,7-cycloheptatrien-1-yl)aminooxoacetic acid ethyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 gm/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - eye/ear
   Reproductive - Specific Developmental Abnormalities - craniofacial
   (including nose and tongue)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   48,A37,1979
 
                            *** END OF RECORD ***